Happy New Year 2026 After 6 weeks of focused work, I successfully deployed a production-grade molecular docking pipeline  (AutoDock Vina + RDKit/OpenMM stack) to Google Cloud Run , backed by Google Cloud Storage  and exposed through a clean API. This is a must-have for anyone who needs to dock compounds at scale without GPUs or Enterprise Hardware, or who uses Kubernetes and/or a DevOps team! Yes, this was built without : A DevOps team Kubernetes Persistent VMs GPUs Enterpris

When I was a kid, one of my favorite toys was a little tin pop-pop boat . It still is!. You lit a candle, the tiny boiler clicked and pulsed, and this cheap toy scooted across a bowl of water like magic. Decades later, I caught myself wondering: What if you scaled that engine up to a size you could steer?  Of course, the answer is you can’t just “scale it up” and expect the same behavior—geometry, heat transfer, and fluid dynamics all gang up on you. The toy works because it

So, I have created a nifty molecular docking engine that can stand shoulder-to-shoulder with big-pharma platforms that cost $100K per year per license. Ok, I admit I don’t have the pedigree of a 20-year vendor track record, and I’m not a biologist, but I am  very good at building complex systems and making them actually run in the real world. For the past 30 years, I’ve shipped and operated mission-critical software for video, networking, and now quantum-enhanced simulation.

Companies like Schrödinger and Atomwise have incredible platforms, but their primary business is selling software and partnering with major pharmaceutical companies. They provide powerful tools  and co-discovery services; their partners own most of the downstream pipeline and wet-lab risk. Schrödinger+1 I built QuantumCURE  with a different mission: not just to rank molecules, but to actually walk a set of compounds all the way into a wet list I own and can defend . In less t

QuantumCURE Fellowship Program Over the past year, I’ve invested more than 3,000 hours  building QuantumCURE Pro  — a platform that brings quantum entropy into drug discovery. My mission is simple: to be useful to humanity  and help accelerate the search for life-saving cancer treatments. Using scientifically validated tools, I’m screening millions of compounds from PubChem with multiple entropy sources, quantum annealing , photonic QRNG seeds , and classical PRNGs . The syst

Let's Dock! It’s been a long, astonishing road since November 2024.That’s when I decided — half out of curiosity, half out of stubbornness — to see if I could connect a quantum random number generator  on my desk to a cloud-based drug discovery engine  that could actually help find new medicines. I didn’t have a corporate lab, a research team, or venture funding. I still don't although I am looking for some to expand and scale up this cool engine I have created. Back then, ju

I am a solo researcher working from my back office, digging into the world of quantum. I work with a handful of QRNG hardware. A year of work with these devices from several hardware developers, has thought me a lot. I know how they behave their streangth and weaknesses, and how to control them using Python. But Randomness from QRNG is not same as Randomness from a Annealing Box like D-Wave quantum system or an Ion Trap system such as ionQ. So let me explain. I am here to sh

By Mansour Ansari — Founder, QuantumLaso LLC I’ve been really busy these days. Not bad for a retired software engineer who officially...

So, last year—right after the Christmas holidays—I set out on a new journey. As a retired software guy, I didn’t want to sit idle. I wanted to build something useful. Something that, in my golden years, could carry value for humanity. That journey led me into the world of quantum random number generators (QRNGs) —tiny devices in USB or PCIe format that don’t just simulate randomness, but harvest it directly from nature . After discovering the technology from CryptaLabs , I wa

What if cancer drug discovery wasn’t limited to billion-dollar pharma labs? From my back office in Oklahoma, I’ve built QuantumCURE  — a molecular docking and retrosynthesis platform that uses AI, open pipelines, and quantum entropy  to explore chemical spaces classical systems often miss. In this video, I explain: Why quantum randomness  changes the search space in simulations How docking with AutoDock Vina  and free protein prep tools (PDBFixer, PDB2PQR) works The role of A

High Performance Molecular Docking System - Citizen Scientist system And yes — I am actively searching for a viable cancer drug lead, with a better chance than most traditional approaches, because my system explores chemical spaces that classical methods often overlook. It’s been almost a year in the making. So far, oh, about 3,340 hours since November 2024. My journey started before that, learning and researching, and that goes back to the COVID-19 era. Built not by a pharm

Version 5 QuantumCURE Pro, Citizen Scientist Desktop and mobile versions --- Breaking Into New Chemical Space I'm excited to announce QuantumCURE v5, the latest and most advanced release of our quantum-powered drug discovery platform. For the first time, QuantumCURE now integrates Bemis–Murcko scaffolding — a powerful computational chemistry technique developed by Guy Bemis and Mark Murcko . This method reduces each compound to its core structural framework, stripping away si

I can answer this because I use all of the above in my project. I use various Quantum Random Number Generator (QRNG) devices to seed my applications with quantum entropy — and they work remarkably well. But randomness, much like a high-performance sports car, comes with different qualities. For example, I use various hardware; my favorite is the https://cryptalabs.com/  USB QRNG hardware. It is a great workhorse. But, allow me to explain a fact: The randomness you get from a

The last time I watched the movie Contact , I was struck by how the extraterrestrials used encoded signals as a way of reaching us. It made for great science fiction. But what if such a thing were truly possible? What if there were a real way to communicate with another intelligent species? If they share the same universe with us, then we already have something in common: quantum fluctuations, entanglement, and the collapse of wave functions.  Even the so-called “void” of int

I’ll admit—I’m a bit disappointed in humanity. For years I’ve been working on a project that pushes into new science, a path I’m deeply passionate about. But it’s not the kind of path most people want to walk. It’s rough, difficult, counterintuitive, and often dismissed as “too sci-fi.” They just don't get it. Investors don’t understand it. Some friends ridicule it. Even seasoned computer people shrug it off. Others laugh because it doesn’t fit inside the comfort zone of high

Hey! You might be wondering — what’s really going on under the hood in the QuantumCURE software I’ve been building? What am I actually doing here? And honestly, what the hell is molecular docking anyway? First things first: if you scroll down and read my disclaimer, you’ll know exactly what I’m not  doing. I’m not a chemist. I’m not a physicist. I don’t work for big pharma. What I am  is a passionate software and systems designer. I understand the moving parts of drug discove

From Tornadoes to Molecules: My Quantum Journey From Tornadoes to Molecules: My Quantum Journey Hi everyone — I’m Mansour Ansari, and if...

Molecular Docking Software Design from a Computer Programmer’s Perspective It took me 7-8 months to build a working drug discovery system...

quantumtornado.org - QuantumCURE drug discovery system. quantumtornado.org QuantumCURE: Quantum-Enhanced Molecular Docking at Scale By...