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QuantumCURE Pro™


CRISP-G as a Symbolic “Mood Alphabet” for Quantum Annealers, A Zaban-Inspired Diagnostic Layer for D-Wave and Other QPUs
When I was a kid, one of my favorite toys was a little tin pop-pop boat . It still is!. You lit a candle, the tiny boiler clicked and pulsed, and this cheap toy scooted across a bowl of water like magic. Decades later, I caught myself wondering: What if you scaled that engine up to a size you could steer? Of course, the answer is you can’t just “scale it up” and expect the same behavior—geometry, heat transfer, and fluid dynamics all gang up on you. The toy works because it

mansour ansari
Dec 7, 202510 min read


My Citizen Scientist Engine Just Passed 478,808 Compounds – And the Hit Rate Is Exactly What I Hoped For
As of today, I have quietly moved 478,808 virtual Compounds through a quantum-enhanced drug discovery machine in my back office in Oklahoma. Today I hit a nice milestone on the Citizen Scientist page of QuantumCURE Pro™ and the numbers made me smile, so I’m sharing them. The Raw Numbers Compounds processed (Citizen Scientist): 478,808 Compounds that made it into the Golden List: 30 Hit rate: What does that mean? In industry, typical virtual screening or HTS hit rates ar

mansour ansari
Dec 5, 20254 min read


I Just Pulled an EGFR Golden List Out of the Quantum Vacuum
QuantumCURE Pro ™ screen shots - Round two of QuantumCURE pro™ software validation is officially in the books. Some people pick up fishing or golf in retirement. I enjoy those too, but for the last few years I’ve been teaching myself quantum computing, cheminformatics, and how to build full cancer drug discovery portals. Why? People ask me that a lot. My answer is simple: why not? I want to be useful, and I still have work to do. I sit in a cold Oklahoma garage, lift heavy

mansour ansari
Dec 2, 20255 min read
How to Create Jobs in the Age of AI With Drug Discovery Technology
I saw an MIT study tonight about AI and job losses, and that is alarming. So, AI can already replace % 11. 7% of US jobs....and workforce, but what the MIT “11.7%” really is: So, MIT + Oak Ridge built a model called the Iceberg Index that looks at: 151M U.S. workers 900+ occupations 32,000+ skills They asked: “With AI that exists today , what fraction of current work tasks could AI technically do?” Their answer: AI is already capable of doing tasks equal to 11.7% of tot

mansour ansari
Nov 30, 20256 min read


How a Quantum Random Number Generator Became the Engine Behind My Drug Discovery & Tornado Forecasting Work
So, I have created a nifty molecular docking engine that can stand shoulder-to-shoulder with big-pharma platforms that cost $100K per year per license. Ok, I admit I don’t have the pedigree of a 20-year vendor track record, and I’m not a biologist, but I am very good at building complex systems and making them actually run in the real world. For the past 30 years, I’ve shipped and operated mission-critical software for video, networking, and now quantum-enhanced simulation.

mansour ansari
Nov 27, 20254 min read
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